Nasal Dosage Forms Containing Natural Female Sex Horomones

Method of Administering Natural Female Sex Horomones

A critical comparison between dosage forms in traditional Persian pharmacy and those reported in current pharmaceutical sciences

There were many natural pharmaceutical dosage forms cited by Persian pharmacists and physicians in the historical pharmacopeias (Qarabadins). This work aimed to perform a comprehensive study on “Qarābādin-e-Sālehi” (1765 A.D.), one of the main Persian pharmaceutical manuscripts defining traditional dosage forms. All traditional dosage forms as well as their definitions, descri...

Nasal Drug Delivery in Traditional Persian Medicine

BACKGROUND Over one hundred different pharmaceutical dosage forms have been recorded in literatures of Traditional Persian Medicine among which nasal forms are considerable. OBJECTIVES This study designed to derive the most often applied nasal dosage forms together with those brief clinical administrations. MATERIALS AND METHODS In the current study remaining pharmaceutical manuscripts of P...

Preparation and Characterisation of Mucoadhesive Nasal Gel of Venlafaxine Hydrochloride for Treatment of Anxiety Disorders

The aim of the present study is to prepare and evaluate mucoadhesive nasal gels of venlafaxine hydrochloride. Mucoadhesive nasal gels were prepared using polymers like carbopol 934 and sodium alginate and characterized in terms of viscosity, texture profile analysis, ex vivo drug permeation profiles and histopathological studies. The results show that values of viscosity, hardness and adhesiven...

Dual sex-specific functions of Drosophila Upstream of N-ras in the control of X chromosome dosage compensation.

Dosage compensation in Drosophila melanogaster involves the assembly of the MSL-2-containing dosage compensation complex (DCC) on the single X chromosome of male flies. Translational repression of msl-2 mRNA blocks this process in females. Previous work indicated that the ubiquitous protein Upstream of N-ras (UNR) is a necessary co-factor for msl-2 repression in vitro. Here, we explore the func...